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Research Page of Yvan Vander Heyden
Posters
[1] Y. Vander Heyden, Ruggedness tests for an HPLC method : comparison
of tests at two and three levels by using two-level Plackett-Burman
designs; 2nd PharmAnalysis Conference, Dusseldorf, Germany, 24-25
April 1995.
[2] P.F. de Aguiar, Y. Vander Heyden and D.L. Massart; Study of
different criteria for the selection of a rugged optimum in HPLC
optimisation, The Balaton Conference on High Performance Separation
Techniques, September 6-8 (1995), Siofok, Hungary.
[3] Y. Vander Heyden, K. De Braekeleer and D.L. Massart; Y.Zhu and
J. Hoogmartens; J. De Beer; Nested designs (nested ANOVA) in ruggedness
testing; 5th International Symposium on Drug Analysis, Leuven, Belgium,
12-15 September 1995.
[4] Y. Vander Heyden and D.L. Massart; P. Nuyten and P. Schoenmakers;
Ruggedness testing of a SEC assay for a low molecular weight polymer
mixture; 5th International Symposium on Drug Analysis, Leuven, Belgium,
12-15 September 1995.
[5] Y. Vander Heyden and D.L. Massart; Y.Zhu and J. Hoogmartens;
J. De Beer; Ruggedness tests on the HPLC assay of the United States
Pharmacopeia XXII for tetracycline.HCl. A comparison of different
columns in an interlaboratory approach; 5th International Symposium
on Drug Analysis, Leuven, Belgium, 12-15 September 1995.
[6] S. Boonkerd, M.R. Detaevernier, Y. Vander Heyden and Y. Michotte;
Determination of the enantiomeric purity of dexfenfluramine by capillary
electrophoresis : use of a Plackett-Burman design for the optimisation
of the separation; 5th International Symposium on Drug Analysis,
Leuven, Belgium, 12-15 September 1995.
[7] Y. Vander Heyden and D.L. Massart, Influence of the sequence
of design experiments on the estimation of effects in case drifting
factors occur; poster presented at the AOAC Lage Landen Symposium,
14 November 1995, Maastricht, The Netherlands.
[8] Y. Vander Heyden and D.L. Massart, Ruggedness tests on the HPLC
assay of the USP XXII for tetracycline.HCL. A comparison of experimental
designs and statistical interpretations, poster presented at the
Chemometrics Symposium Solvay, 17 November 1995, Brussels, Belgium.
[9] Y. Vander Heyden, P. Vankeerberghen, M. Novic, J. Zupan and
D.L. Massart; The application of Kohonen neural networks for the
diagnosis of calibration problems from atomic absorption spectrometry;
poster presented at the CAC'96 International Conference (Tarragona,
Spain) 25-29 June 1996.
[10] Y. Vander Heyden, A. Bourgeois and D.L. Massart, Influence
of the sequence of design experiments in a ruggedness test on the
estimation of effects when drifting factors occur; poster presented
at the CAC'96 International Conference (Tarragona, Spain) 25-29
June 1996.
[11] Y. Vander Heyden, F. Questier and D.L. Massart, A ruggedness
test strategy; poster presented at the CAC'96 International Conference
(Tarragona, Spain) 25-29 June 1996.
[12] P.F. de Aguiar, Y. Vander Heyden and D.L. Massart, Study of
different criteria for the selection of a rugged optimum in HPLC
optimisation; poster presented at the CAC'96 International Conference
(Tarragona, Spain) 25-29 June 1996.
[13] W. Penninckx, Y. Vander Heyden, D.L. Massart and J. Smeyers-Verbeke,
Nested designs to estimate the precision in atomic absorption spectrometry,
poster presented at the CAC'96 International Conference (Tarragona,
Spain) 25-29 June 1996.
[14] E. Bouveresse, S.C. Rutan, Y. Vander Heyden, W. Penninckx and
D.L. Massart, Stability of the instrumental response of NIR spectrometers
over time, poster presented at 2nd Chemometrics Symposium, Arenberg
Castle, Heverlee, Belgium, 27 September 1996.
[15] W. Prus, Y. Vander Heyden, P. Vankeerberghen, P. Kus, D.L.
Massart and T. Kowalska; A comparison of the performance of models
of solute retention in the RP-HPLC system with the chemically bonded
3-cyanopropyl stationary phase; poster presented at CC'97 Conferentia
Chemometrica, Budapest, Hungary, 21-23 August 1997.
[16] W. Prus, Y. Vander Heyden, P. Kus, D.L. Massart and T. Kowalska;
Statistical comparison of selected RP-HPLC retention models; poster
presented at CC'97 Conferentia Chemometrica, Budapest, Hungary,
21-23 August 1997.
[17] W. Prus, Y. Vander Heyden, D.L. Massart and T. Kowalska; A
comparison of the performance of models of solute retention in the
NP-HPLC system with the chemically bonded 3-cyanopropyl stationary
phase; poster presented at CC'97 Conferentia Chemometrica, Budapest,
Hungary, 21-23 August 1997
[18] F. Questier, Y. Vander Heyden and D.L. Massart; RTS, a computer
program for the experimental set-up and interpretation of ruggedness
tests; poster presented at CC'97 Conferentia Chemometrica, Budapest,
Hungary, 21-23 August 1997
[19] Y. Vander Heyden, C. Maes, E. Roets, J. Hoogmartens and D.L.
Massart; Interlaboratory study on two HPLC assays for tylosin tartrate;
presented at the 7th Meeting on Recent Developments in Pharmaceutical
Analysis (RDPA'97), September 16-20, 1997, Island of Elba, Italy.
[20] Y. Vander Heyden and D.L. Massart, Supersaturated designs in
ruggedness testing; presented at 3rd Chemometrics Symposium, 17
October 1997, Gembloux, Belgium
[21] J.J. Cirunay, Y. Vander Heyden and J. Plaizier-Vercammen, Investigation
on the photostability of calcilpotriol in selected solvents and
in the presence of a sunscreen, presented at Drug Analysis '98 Symposium,
11-15 May 1998, Brussels, Belgium.
[22] F. Questier, Y. Vander Heyden and D.L. Massart; RTS, a software
package for the experimental set-up and interpretation of ruggedness
tests, presented at Drug Analysis '98 Symposium, 11-15 May 1998,
Brussels, Belgium.
[23] Y. Vander Heyden, H. Spapen, J. Van Brempt and D.L. Massart,
Method development and validation of an HPLC assay with post-column
derivatisation for N-acetylcysteine in plasma, presented at Drug
Analysis '98 Symposium, 11-15 May 1998, Brussels, Belgium.
[24] Y. Vander Heyden, H. Van Roost, F. Zhou, C. Vervaet, J. P.
Remon and D.L. Massart; Response modelling in the proces optimisation
of matrix pellets based on microcrystalline waxes and starch derivatives,
presented at Drug Analysis '98 Symposium, 11-15 May 1998, Brussels,
Belgium.
[25] M.G. Vargas, Y. Vander Heyden, M. Maftouh and D.L. Massart;
Rapid enantiomeric separation of b-blockers by capillary electrophoresis
using experimental design approach, presented at 10th International
Symposium of Chiral Discrimiation (ISCG'98), Vienna, Austria, 30
August- 04 September 1998.
[26] J.R. Torres, Y. Vander Heyden, M.G. Vargas, M. Maftouh and
D.L. Massart; KBS, a knowledge based system for chiral separations,
presented at 10th International Symposium of Chiral Discrimiation
(ISCG'98), Vienna, Austria, 30 August- 04 September 1998.
[27] E. Hund, Y. Vander Heyden, D.L. Massart and J. Smeyers-Verbeke;
Evaluation of the H-point standard additions method (HPSAM) and
of the generalized H-point standard additions method (GHPSAM) for
the UV analysis of binary mixtures, presented at Compana'98 incorporating
LIMS, Duisburg, Germany, 15-18 September 1998.
[28] Y. Vander Heyden, M. Jimidar, E. Hund, N. Niemeijer, R. Peeters,
J. Smeyers-Verbeke, D.L. Massart and J. Hoogmartens; Determination
of system suitability limits with a robustness test, presented at
4th Chemometrics Symposium, 20 November 1998, Tervuren
[29] E. Hund, Y. Vander Heyden, M. Haustein, D.L. Massart and J.
Smeyers-Verbeke, Application of an asymmetrical factorial design
in the robustness test of an HPLC procedure, presented at 4th Chemometrics
Symposium, 20 November 1998, Tervuren
[30] A. De Troyer, V. Schoonjans, F. Questier, Y. Vander Heyden,
A.P. Borosy and D.L. Massart; Classification de substances pharmaceutiques
sur la base de données chromatographiques; presented at the
Congrès SEP 99 (Congrès sur les Techniques Séparatives),
30 March - 1 April 1999, Lyon, France
[31] E. Hund, Y. Vander Heyden, M. Haustein, D.L. Massart, J. Smeyers-Verbeke;
Comparison of different criteria to decide on the significance of
effects in a robustness test of an HPLC procedure with an asymmetrical
factorial design; presented at the congres ANAKON'99, 7-10 April
1999, Konstanz, Germany.
[32] E. Hund, Y. Vander Heyden, D.L. Massart and J. Smeyers-Verbeke;
Ruggedness testing for pharmaceuticals: comparison of staggered-nested
and fully-nested designs, presented at the 5th chemometrics symposium
(KVCV), 22 October 1999, Machelen, Belgium.
[33] Y. Vander Heyden, A. Nijhuis, J. Smeyers-Verbeke, B.G.M. Vandeginste
and D.L. Massart; Guidance for robustness/ruggedness tests in method
validation, poster presentation at PBA2000, 11th International Symposium
on Pharmaceutical and Biomedical Analysis, May 14-18, 2000, Basel,
Switzerland
[34] E. Hund, Y. Vander Heyden, D.L. Massart and J. Smeyers-Verbeke,
Derivation of system suitability criteria from a ruggedness test,
poster presentation at PBA2000, 11th International Symposium on
Pharmaceutical and Biomedical Analysis, May 14-18, 2000, Basel,
Switzerland
[35] P. Petit, Y. Vander Heyden, C. Nelissen, D.L. Massart, B. Rombaut,
Increase of interdisciplinarity in pharmacy education at the Vrije
Universiteit Brussel, Belgium; poster presented at the European
Conference Orienting pharmaceutical education and profession to
meet the needs of the future; 11-12 may 2000, and Satellite Symposium
Implementation of pharmaceutical care into the curriculum; 13 may
2000; Lisbon Portugal.
[36] P. Petit, Y. Vander Heyden, C. Nelissen, D.L. Massart, B. Rombaut,
Increase of interdisciplinarity in pharmacy education at the Vrije
Universiteit Brussel, Belgium; poster presented at the Second international
conference on Problem-based Learning in higher education; September
17-20, 2000, Linköping, Sweden.
[37] C. Vannecke, E. Van Gijseghem, M.S. Bloomfield, Y. Vander Heyden
and D.L. Massart; Evaluation of chemical reaction parameters using
experimental design in the development of a generic method to determine
compounds with a secondary amine or amide function, poster presentation
at the 7th International Conference of Chemometrics in Analytical
Chemistry, 16-20 October 2000, Antwerp, Belgium.
[38] S. Lauwers, Y. Vander Heyden, D.L. Massart and B. Rombaut,
Screening of an enterovirus specific RP-PCR ELISA method for the
quantification of enterovirus genomes in human body fluids by means
of a three-level experimental design, poster presentation at the
7th International Conference of Chemometrics in Analytical Chemistry,
16-20 October 2000, Antwerp, Belgium.
[39] J. Luypaert, Y. Vander Heyden and D.L. Massart; Influence of
NIR pre-processing methods on classification of clinical study lots
of a dermatological cream, poster presentation at the 7th International
Conference of Chemometrics in Analytical Chemistry, 16-20 October
2000, Antwerp, Belgium.
[40] E. Smet, L. Staelens, Y. Vander Heyden, H.Y. Aboul-Enein, G.
Van der Weken, A.M. García-Campaña and W.R.G. Baeyens,
Application of multicriteria decision making approaches for the
separation optimisation of some non-steroidal anti-inflammatory
drugs on an avidin chiral stationary phase, poster presentation
at the 7th International Conference of Chemometrics in Analytical
Chemistry, 16-20 October 2000, Antwerp, Belgium.
[41] Y. Vander Heyden, F. Estienne and D.L. Massart, Supersaturated
designs: attempts to estimate factor effects, poster presentation
at the 7th International Conference of Chemometrics in Analytical
Chemistry, 16-20 October 2000, Antwerp, Belgium.
[42] B. Chimanuka, G. François, G. Timperman Y. Vander Heyden,
J. Holenz, G. Bringmann and J. Plaizier-Vercammen; Monitoring antimalarial
drugs in efficacy through differential parasitaemia and morphological
changes: case of dioncophylline B, chloroquine and artemether; International
colloquium, Moving targets, parasites, resistance and access to
drugs, Institute of Tropical Medicine, Antwerp, 4-6 december 2000.
[43] C. Vannecke, F. Questier, Y. Vander Heyden and D.L. Massart;
Web publishing in project based education, poster presentation at
the "New Orientations of Teaching" congress, VUB, Brussels,
Belgium, May 4-6, 2001.
[44] Y. Vander Heyden, C. Vannecke, E. Van Gyseghem, Evaluation
of students in project based education, poster presentation at the
"New Orientations of Teaching" congress, VUB, Brussels,
Belgium, May 4-6, 2001.
[45] C. Perrin, N. Matthijs, Y. Vander Heyden, M. Maftouh, D.L.
Massart; Chiral separatins of drugs using polysaccharide stationary
phases in normal and reversed phase liquid chromatography, poster
presentation at HPLC 2001, June 17-22, 2001, Maastricht, The Netherlands.
[46] Y. Vander Heyden, A. Nguyen Minh Nguyet, M. Detaevernier, D.L.
Massart, J. Plaizier-Vercammen, Simultaneous HPLC determination
of ketoconazole and formaldehyde in a shampoo: method development
and validation; poster presentation at HPLC 2001, June 17-22, 2001,
Maastricht, The Netherlands.
[47] N. Matthijs, C. Perrin, D.L. Massart and Y. Vander Heyden;
Fast method development of chiral separation using chromatography
and capillary electrophoresis; poster presentation at HPLC 2001,
June 17-22, 2001, Maastricht, The Netherlands.
[48] A. Detroyer, I. Cambré, Y. Vander Heyden and D.L. Massart;
Comparing recently introduced chromatographic and electrophoretic
methods in a quantitative structure-retention relationship context;
poster presentation at HPLC 2001, June 17-22, 2001, Maastricht,
The Netherlands.
[49] T. Iványi, D. Visky, J. De Beer, E. Roets, J. Hoogmartens,
D.L. Massart and Y. Vander Heyden; Characterisation of Stationary
Phases. Survey of the Data Analysis, Possibilities for Column Clustering
based on a Minimal Number of Column Tests, poster presentation at
HPLC 2001, June 17-22, 2001, Maastricht, The Netherlands.
[50] Y. Vander Heyden, A. Nguyen Minh Nguyet, L. Tallieu, J. Plaizier-Vercammen,
D.L. Massart; Validation of an HPLC method on short columns to assay
ketoconazole and formaldehyde in shampoo, poster presentation at
HPLC 2001, June 17-22, 2001, Maastricht, The Netherlands.
[51] E. van Gyseghem, D.L. Massart and Y. Vander Heyden; Orthogonal
chromatographic systems for the characterisation of impurities in
drugs; poster presentation at HPLC 2001, June 17-22, 2001, Maastricht,
The Netherlands.
[52] Visky D., Iványi T., Vander Heyden Y., De Beer J., Kovács
Zs., Noszál B., Roets E., Massart D. L., Hoogmartens J.,
Characterisation of 71 PRLC C18 Columns by Chromatographic Tests:
Interlaboratory Study; poster presentation at Balaton Symposium
2001 on High Performance Separation Methods, September 2-4, 2001,
Siófok, Hungary.
[53] Y. Vander Heyden, S.T. Popovici and P.J. Schoenmakers; Evaluation
of calibration curves from size exclusion chromatography; poster
presentation at the yearly meeting of the "Studiegroep Analytische
Scheikunde", October 29-30, 2001, Lunteren, Nederland.
[54] Y. Vander Heyden, S.T. Popovici and P.J. Schoenmakers; Evaluation
of size-exclusion chromatography calibration curves; poster presentation
at the HTC-7 - International Symposium on Hyphenated Techniques
in Chromatography, February 6-8, 2001, Bruges, Belgium.
[55] D. Mangelings, C. Perrin, D.L. Massart and Y. Vander Heyden,
Enantioseparations of basic compounds using cyclodextrines: comparison
of capillary electrophoresis and capillary electrochromatography,
poster presentation at Drug Analysis 2002, April 22-25, 2002, Bruges,
Belgium.
[56] P. Dehouck, J. Smeyers-Verbeke, D.L. Massart, Y. Vander Heyden,
J. Crommen, Ph. Hubert, R. Marini, A. Van Schepdael, E. Roets, O.S.N.M.
Smeets, G. Decristoforo, J. De Beer, M.G. Quaglia, J.L. Veuthey,
O. Estevenon, J. Hoogmartens; Determination of uncertainty in analytical
measurements: collaborative study of the analysis of phenoxymethylpenicillin;
poster presentation at Drug Analysis 2002, April 22-25, 2002, Bruges,
Belgium.
[57] W.R.G. Baeyens, G. Van der Weken, Y. Vander Heyden, E. Smet,
V. Van Bossche, Investigation of the chiral separation of cisapride
on Chiralcel OJ and OJ-R columns; poster presentation at Drug Analysis
2002, April 22-25, 2002, Bruges, Belgium.
[58] A.M. Van Nederkassel, A. Aerts, D.L. Massart and Y. Vander
Heyden, Fast separations on monolithic silica columns: minimization
of analysis time and robustness of the separations, poster presentation
at Drug Analysis 2002, April 22-25, 2002, Bruges, Belgium.
[59] E. Vasbinder, G. Van der Weken, Y. Vander Heyden, W.R.G. Baeyens,
T. Vankeirsbilck, A. Vercauteren, A. De Bunne and J.P. Remon; Application
of a chromolith Speedrod RP-18e HPLC column: quantitative determination
of p-aminosalicylic acid and degradation product m-aminophenol in
pellets; poster presentation at Drug Analysis 2002, April 22-25,
2002, Bruges, Belgium.
[60] E. Vasbinder, G. Van der Weken, Y. Vander Heyden, W.R.G. Baeyens,
T. Vankeirsbilck, A. Vercauteren, A. De Bunne and J.P. Remon; Comparison
of a robustness testing method on a chromolith speedrod rP-18e HPLC
column and a conventional reversed phase cartridge column for the
determination of p-aminosalicylic acid and its degradation product;
poster presentation at Drug Analysis 2002, April 22-25, 2002, Bruges,
Belgium.
[61] C. Perrin, N. Matthijs, M. Maftouh, D.L. Massart and Y. Vander
Heyden, Development of generic strategies for the chiral separation
of pharmaceuticals, poster presentation at HPLC 2002, June 2-7,
2002, Montreal, Canada.
[62] A. Van Nederkassel, A. Aerts, D.L. Massart and Y. Vander Heyden,
Fast separations on monolithic silica columns: minimization of analysis
time and robustness of the separations, poster presentation at HPLC
2002, June 2-7, 2002, Montreal, Canada.
[63] A. Detroyer, K. Reynaert, Y. Vander Heyden and D.L. Massart,
Evaluating monolithic columns with or without a micellar medium
in a QSRR-QRAR context, poster presentation at HPLC 2002, June 2-7,
2002, Montreal, Canada.
[64] S. Popovici, Y. Vander Heyden and P.J. Schoenmakers, Polystyrene
standard polydispersity contribution to band broadening in size-exclusion
chromatography, poster presentation at HPLC 2002, June 2-7, 2002,
Montreal, Canada.
[65] A. Nguyen Minh Nguyet, L. Tallieu, J. Smeyers-Verbeke, D.L.
Massart and Y. Vander Heyden, Method comparison: short and long-column
HPLC assays of ketoconazole and formaldehyde in shampoo, poster
presentation at HPLC 2002, June 2-7, 2002, Montreal, Canada.
[66] E. Van Gyseghem, M. Daszykowski, F. Questier, Y. Vander Heyden,
D.L. Massart; Determining orthogonal chromatographic systems prior
to the development of methods to characterise impurities in drugs,
poster presentation at the 24th International Symposium on Chromatography,
Leipzig, Germany, September 15-20, 2002.
[67] E. Van Gyseghem, I. Crosiers, S. Gourvenec, Y. Vander Heyden,
D.L. Massart; Application of HPLC-DAD for determining orthogonal
chromatographic systems to characterise impurities in drugs, poster
presentation at the 24th International Symposium on Chromatography,
Leipzig, Germany, September 15-20, 2002.
[68] R. Put, C. Perrin, Y. Vander Heyden and D.L. Massart; Classification
and Regression Tree Analysis (CART) for prediction of retention
classes in RPLC; poster presentation at the 24th International Symposium
on Chromatography, Leipzig, Germany, September 15-20, 2002.
[69] S.T. Popovici, Y. Vander Heyden, W.Th. Kok and P.J. Schoenmakers,
Band broadening in Size-Exclusion Chromatography, poster presentation
at the 24th International Symposium on Chromatography 2002, September
15 - 20, 2002, Leipzig, Germany.
[70] A. Detroyer, K. Reynaert, Y. Vander Heyden and D.L. Massart;
Evaluation of monolithic columns with and without a micellar medium
in a QSRR-QSAR context, poster presentation at the 24th International
Symposium on Chromatography 2002, September 15 - 20, 2002, Leipzig,
Germany.
[71] E. Van Gyseghem, A. Elkihel, M. Jimidar, M. Daszykowski, F.
Questier, D.L. Massart and Y. Vander Heyden, Hierarchical 2-way
clustering techniques to select subsets of chromatographic systems
and substances, poster presented at the 7th Chemometrics Symposium,
4 december 2002, Machelen, Belgium.
[72] Y. Vander Heyden, S.T. Popovici, B.B.P. Staal, and P.J. Schoenmakers
Contribution of the polymer standards' polydispersity to the observed
band broadening in size-exclusion chromatography, poster presentation
at the Symposium "Separation and Characterization of Natural
and Synthetic Macromolecules", 5-7 February 2003, Amsterdam,
The Netherlands.
[73] D. Mangelings, N. Hardies, M. Maftouh, C. Suteu, D.L. Massart,
Y. Vander Heyden, Screening strategy in capillary electrochromatography
for chiral pharmaceuticals using polysaccharide stationary phases,
HPLC 2003: 27th Symposium on High Performance Liquid Phase Separations
and Related Techniques, 15-19 June 2003, Nice-France.
[74] N. Matthijs, C. Perrin, D.L. Massart, M. Maftouh, Y. Vander
Heyden, Electrophoretic separation of chiral compounds using dual
cyclodextrin systems, HPLC 2003: 27th Symposium on High Performance
Liquid Phase Separations and Related Techniques, 15-19 June 2003,
Nice-France.
[75] N. Matthijs, C. Perrin, D.L. Massart, M. Maftouh, Y. Vander
Heyden, Strategic method development for the separation of chiral
pharmaceutical compounds, HPLC 2003: 27th Symposium on High Performance
Liquid Phase Separations and Related Techniques, 15-19 June 2003,
Nice-France.
[76] A. Detroyer, S. Stockbroeckx, Y. Vander Heyden and D.L. Massart;
Selecting fast permeability assessing methods for high-throughput
screening; HPLC 2003: 27th Symposium on High Performance Liquid
Phase Separations and Related Techniques, 15-19 June 2003, Nice-France.
[77] Tímea Iványi, Kornélia Pál, István
Lázár, Yvan Vander Heyden, D. L. Massart, Application
of macrocycle type molecules as chiral selector modifiers in capillary
electrophoresis, poster at the 28th International Conference on
Solution Chemistry, August 23-28, 2003, Debrecen, Hungary.
[78] D. Mangelings, N. Hardies, M. Maftouh, C. Suteu, D.L. Massart,
Y. Vander
Heyden, Screening strategy in capillary electrochromatography for
chiral pharmaceuticals using polysaccharide stationary phases, KVCV
Symposium, Fifth Belgian CE-users Group Meeting, "CE-MS in
Pharmaceutical Development and Medical Protein Research, October
16th, 2003, Janssen Pharmaceutica, Beerse, Belgium
[79] N. Matthijs, C. Perrin, D.L. Massart, M. Maftouh, Y. Vander
Heyden, Electrophoretic separation of chiral compounds using dual
cyclodextrin systems, KVCV Symposium, Fifth Belgian CE-users Group
Meeting, "CE-MS in Pharmaceutical Development and Medical Protein
Research, October 16th, 2003, Janssen Pharmaceutica, Beerse, Belgium
[80] Tímea Iványi, Kornélia Pál, István
Lázár, D.L. Massart and Yvan Vander Heyden, A potentially
biologically active tetraozadiaza-crown ether derivative as chiral
selector in capillary electrophoresis, Fifth Belgian CE-users Group
Meeting, "CE-MS in Pharmaceutical Development and Medical Protein
Research, October 16th, 2003, Janssen Pharmaceutica, Beerse, Belgium
[81] J. Elek, T. Iványi, D-L Massart, I. Lázár
and Y. Vander Heyden, Capillary-electrophoretic enantioselective
separation of tryptophane- and tyrosine-methylesters in dual selector
systems with tetraoxadiaza-crown ether derivatives and cyclodextrins
using capillary-electrophoresis, Fifth Belgian CE-users Group Meeting,
"CE-MS in Pharmaceutical Development and Medical Protein Research,
October 16th, 2003, Janssen Pharmaceutica, Beerse, Belgium
[82] E. Van Gyseghem, M. Jimidar, R. Sneyers, D. Redlich, E. Verhoeven,
D.L. Massart and Y. Vander Heyden, Selection of an orthogonal subset
of reversed phase HPLC columns on LC-MS-DAD, poster presented at
Advances in Chromatography and Electrophoresis - Conferentia Chemometrica
(ACE&CC) 2003 - 27-29 October 2003 - Budapest - Hungary
[83] A.M. Van Nederkassel, D.L. Massart and Y. Vander Heyden, Correlation
Optimized Warping: a pre-processing method to align fast chromatograms
in order to allow further chemometic treatment of the data; poster
presented at Advances in Chromatography and Electrophoresis - Conferentia
Chemometrica (ACE&CC) 2003 - 27-29 October 2003 - Budapest -
Hungary
[84] J. Elek, T. Iványi, D-L Massart, I. Lázár
and Y. Vander Heyden, The enantioselective CE separation of tryptophane-
and tyrosine-methylesters in dual selector systems with tetraoxadiaza-crown
ether derivatives and cyclodextrins, poster presented at Advances
in Chromatography and Electrophoresis - Conferentia Chemometrica
(ACE&CC) 2003 - 27-29 October 2003 - Budapest - Hungary
[85] T. Iványi, K. Pál, I. Lázár, D.L.
Massart and Y. Vander Heyden, Modification of the enantioselective
effect of different cyclodextrins using tetraoxadiaza-crown ether
derivatives as chiral selector modifiers in capillary electrophoresis;
poster presented at Advances in Chromatography and Electrophoresis
- Conferentia Chemometrica (ACE&CC) 2003 - 27-29 October 2003
- Budapest - Hungary.
[86] R. Put, D.L. Massart and Y. Vander Heyden; Classification and
regression tree (CART) and multivariate regression tree (MRT) analysis
for the selection of orthogonal and analogeous chromatographic systems;
poster presented at Advances in Chromatography and Electrophoresis
- Conferentia Chemometrica (ACE&CC) 2003 - 27-29 October 2003
- Budapest - Hungary.
[87] R. Put, D.L. Massart and Y. Vander Heyden; RPLC retention prediction
using multivariate adaptive regression splines (MARS); poster presented
at Advances in Chromatography and Electrophoresis - Conferentia
Chemometrica (ACE&CC) 2003 - 27-29 October 2003 - Budapest -
Hungary.
[88] D. Visky, P. Dehouck, E. Adams, Y. Vander Heyden, T. Ivanyi,
P. Baten, J. De Beer, Z. Kovacs, B. Noszal, E. Roets, D.L. Massart,
J. Hoogmartens; Characterisation of reversed-phase liquid chromatographic
columns by chromatographic tests. Part 1: Rational column classification
by a minimal number of column test parameters; poster presented
at HTC-8, 4-6 February 2004, Bruges - Belgium.
[89] P. Dehouck, D. Visky, Y. Vander Heyden, E. Adams, Z Kovacs,
B. Noszal, D.L. Massart, J Hoogmartens; Characterization of reversed-phase
liquid chromatographic columns by chromatographic tests. Part II:
Comparing column classification based on chromatographic parameters
and column performance for the separation of acetylsalicylic acid
and related compounds; poster presented at HTC-8, 4-6 February 2004,
Bruges - Belgium.
[90] D. Mangelings, M. Maftouh, D.L. Massart and Y. Vander Heyden;
Differences between normal-phase and reversed-phase polysaccharide
chiral stationary phases in capillary electrochromaotgraphic separations;
poster presented at HPCE2004, 8-12 february 2004, Salzburg, Austria.
[91] T. Iványi, K. Pál, I. Lázár, D.L.
Massart and Y. Vander Heyden, A potentially biologically active
tetraozadiaza-crown ether derivative as chiral selector in capillary
electrophoresis, poster presented at HPCE2004, 8-12 february 2004,
Salzburg, Austria.
[92] J. Elek, T. Iványi, D-L Massart and Y. Vander Heyden,
Enantioselective separation optimisation for tryptophane- and tyrosine-methylesters
using capillary electrophoresis and dual selector systems with tetraoxadiaza-crown
ether derivatives and cyclodextrins, poster presented at HPCE2004,
8-12 february 2004, Salzburg, Austria.
[93] M. Daszykowski, P. Wiczling, M.P. Marszall, T. Baczek, R. Kaliszan,
P. Juszczyk, K. Wisniewska, Z. Grzonka and Y. Vander Heyden, Modeling
retention of peptides in terms of molecular descriptors, XXVIIIth
symposium 'Chromatographic Methods of Investigating the Organic
Compounds, 7-9 june 2004, Katowice - Szczyrk, Poland
[94] R. Put, M. Jimidar, E. Van Gyseghem, D.L. Massart and Y. Vander
Heyden; The selection of orthogonal reversed-phase HPLC systems
by multivariate regression trees, XXVIIIth symposium 'Chromatographic
Methods of Investigating the Organic Compounds, 7-9 june 2004, Katowice
- Szczyrk, Poland
[95] B. Dejaegher, J. Smeyers-Verbeke, D.L. Massart, Y. Vander Heyden,
The variance of screening- and supersaturated- design results as
a measure for the robustness of a method, 9th International Conference
on Chemometrics in Analytical Chemistry (CAC-2004) - September 20-23,
2004 - Instituto Superior Técnico - Lisbon - Portugal
[96] N. Matthijs, M. Maftouh, D.L. Massart and Y. Vander Heyden;
Polar organic mode-based chromatographic chiral screening strategy
on polysaccharide columns, 25th International Symposium on Chromatography,
4-8 october 2004, Paris, France
[97] A.M. Van Nederkassel, D.L. Massart and Y. Vander Heyden; Antioxidant
activity of green tea extracts estimated from chromatograms using
partial least squares regression and a colorimetric reference method,
25th International Symposium on Chromatography, 4-8 october 2004,
Paris, France
[98] D. Mangelings, I. Tanret, M. Maftouh, D.L. Massart and Y. Vander
Heyden; Development of a screening strategy in capillary electrochromatography
to evaluate the enatioselective separation of acidic drugs on polysaccharide
stationary phases, 25th International Symposium on Chromatography,
4-8 october 2004, Paris, France
[99] E. Deconinck, T. Hancock, D. Coomans, D.L. Massart, Y. Vander
Heyden, Classification And Regression Trees (CART) in the prediction
of gastro-intestinal absorption of pharmaceuticals, 4th symposium
on Drug Discovery, April 7-8th 2005, UA, Antwerp, Belgium
[100] E. Deconinck, Q.S. Xu, R. Put, D. Coomans, D.L. Massart, Y.
Vander Heyden, Prediction of gastro-intestinal absorption using
Miltivariate Adaptive Regression Splines, 4th symposium on Drug
Discovery, April 7-8th 2005, UA, Antwerp, Belgium
[101] A. Detroyer,E. Deconinck, D.L. Massart, Y. Vander Heyden,
Introduction of "fast" micellar liquid chromatography
for QSRR-QRAR, 4th symposium on Drug Discovery, April 7-8th 2005,
UA, Antwerp, Belgium
[102] B. Dejaegher, J. Smeyers-Verbeke, Y. Vander Heyden, Identifying
significant effects in experimental designs for robustness testing:
randomization tests versus the algorithm of Dong, 30 ans de Méthodologie
de la Recherche Expérimentale - June 2-3, 2005 - Aix en Provence
- France
[103] E. Deconinck, Q.S. Xu, R. Put, D. Coomans, D.L. Massart, Y.
Vander Heyden; Prediction of gastro-intestinal absorption using
Multivariate Adaptive Regression Splines, Symposium on In silico
ADME-Tox: Design of bioactive Compounds, June 8th-9th, SCI Intenational
Headquarters, London, UK
[104] A.M. van Nederkassel, V. Vijverman, D.L. Massart and Y. Vander
Heyden; Development of a Gingko biloba fingerprint chromatogram
with UV and ELS detection and optimization of the ELSD operating
conditions, poster presentation at the 29th symposium 'Chromatographic
methods of investigating the organic compounds', June 8-10, 2005,
Katowice-Szczyrk, Poland.
[105] A.M. van Nederkassel, M. Daszykowski, D.L. Massart and Y.
Vander Heyden; Antioxidant acticity of green tea extracts estimated
from chromatograms using partial least squares regression and a
colorimetric reference method, poster presentation at the 29th symposium
'Chromatographic methods of investigating the organic compounds',
June 8-10, 2005, Katowice-Szczyrk, Poland.
[106] Y. Vander Heyden, N. Matthijs, D. Mangelings, M. Maftouh and
D.L. Massart; Polar organic mode-based chromatographic chiral screening
strategy on polysaccharide columns; poster presentation at the 29th
symposium 'Chromatographic methods of investigating the organic
compounds', June 8-10, 2005, Katowice-Szczyrk, Poland.
[107]A.M. van Nederkassel, V. Vijverman, D.L. Massart and Y. Vander
Heyden; Development of a Gingko biloba fingerprint chromatogram
with UV and ELS detection and optimization of the ELSD operating
conditions, poster presented at the 29th International Symposium
on High Performance Liquid Phase Separations and Related Techniques
(HPLC2005), June 26-30, 2005, Stockholm, Sweden.
[108] A.M. van Nederkassel, M. Daszykowski, D.L. Massart and Y.
Vander Heyden; Antioxidant acticity of green tea extracts estimated
from chromatograms using partial least squares regression and a
colorimetric reference method, poster presented at the 29th International
Symposium on High Performance Liquid Phase Separations and Related
Techniques (HPLC2005), June 26-30, 2005, Stockholm, Sweden.
[109] Y. Vander Heyden, N. Matthijs, D. Mangelings, M. Maftouh and
D.L. Massart; Polar organic mode-based chromatographic chiral screening
strategy on polysaccharide columns; poster presented at the 29th
International Symposium on High Performance Liquid Phase Separations
and Related Techniques (HPLC2005), June 26-30, 2005, Stockholm,
Sweden.
[110] A.M. Van Nederkassel, C.J. Xu, P. Lancelin, J.R. Desmurs,
D.A. MacKenzie, N.J. Walton, F. Bensaid, M. Lees, G.J. Martin, D.L.
Massart, J. Smeyers-Verbeke, Y. Vander Heyden; Chemometrical treatment
of UV and MS vanillin fingerprint chromatograms: signal pretreatment
and classification by PCA; poster presented at the 29th International
Symposium on High Performance Liquid Phase Separations and Related
Techniques (HPLC2005), June 26-30, 2005, Stockholm, Sweden.
[111] N. Matthijs, M. Maftouh, D.L. Massart and Y. Vander Heyden;
Development of a software tool 'Chiral KBS' for chiral method development
in different separation techniques; poster presented at the 29th
International Symposium on High Performance Liquid Phase Separations
and Related Techniques (HPLC2005), June 26-30, 2005, Stockholm,
Sweden.
[112] P. Kawczak, A. Detroyer, Y. Vander Heyden, A. Nasal, A. Drabczyñska,
K. Kieæ-Kononowicz; Application of micellar liquid chromatography
(MLC) to determine lipophilicity of new purindione derivatives of
potential anticonvulsant activity; Joint Meeting on Medicinal Chemistry
in Vienna, Austria, June 20-23, 2005.
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